(placeholder)
(placeholder)

Chemistry / Supramolecular / System / Biology

Publications

(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)
(placeholder)

67. "Boron Clusters as Broadband Membrane Carriers." Barba-Bon, A.; Salluce, G.; Lostalé-Seijo, I.; Assaf, K. I.; Hennig, A.; Montenegro, J.; Nau, W.  Nature, 2022, 603, 637–642.

66. "Self-Healing Cyclic Peptide Hydrogels" Bayon-Fernández, A.; Méndez-Ardoy, A.;  Álvarez-Lorenzo, C.; Granja, J.; Montenegro, J. J. Mat. Chem. B, 2023, 11, 606-617.

65. "A 3D Peptide/[60]Fullerene Hybrid for Multivalent Recognition" Gallego, I.; Ramos-Soriano, J.; Méndez-Ardoy, A.; Cabrera-González, J.; Lostalé-Seijo, I.; Illescas, B. M.; Reina, J. J.; Martín, N.; Montenegro, J. Angew. Chem. Int. Ed., 2022, 61, e202210043.

64. “Dynamic Nanosurface Reconfiguration by Host-Guest Supramolecular Intereactions" Fernádez-Caro, H.; ,Méndez-Ardoy, A.; Montenegro, J. Nanoscale, 2022,14, 3599-3608.

62. “Glycan Shields for Penetrating Peptides"  Gallego, I.; Montenegro, J. Chem. Commun. 2022, 58, 1394-1397.

63. “Bottom-up supramolecular assembly in two dimensions"  Insua, I.; Bergueiro, J.; Méndez-Ardoy, A.; Lostalé-Seijo, I.; Montenegro, J. Chem. Sci. 2022, 13, 3057–3068.

61. "Cyclization and Self-Assembly of Cyclic Peptides". Méndez-Ardoy A.; Insua, I.; Granja, J.; Montenegro, J. Methods Mol Biol. 2022; 2371:449-466. doi: 10.1007/978-1-0716-1689-5_24. PMID: 34596863.

60. “1D alignment of proteins and other nanoparticles by using reversible covalent bonds on cyclic peptide nanotubes"   Priegue, J.M.; Louzao, I.; Gallego, I.; Montenegro, J. Granja, J. R.; Org. Chem. Front. 2022, 9, 1226-1233.


59. “Supramolecular fibrillation of peptide amphiphiles induces environmental responses in aqueous droplets" Booth, R.; Insua, I.; Ahmed, S.; Rioboo, A.; Montenegro, J.; Nature Communications 2021, 12, 6421.

58. “The Emergence of Order: A Closer Look at Peptide Assembly and Its Complexity" Mendez-Ardoy, A.; Bergueiro, J.; Montenegro, J.; Matter 2021, 10, 3081-3083.

57. “Short Oligoalanine Helical Peptides for Supramolecular Nanopore Assembly and Protein Cytosolic Delivery" Pazo, M.; Salluce, G.; Lostalé-Seijo, I.; Juanes, M., Gonzalez, F.; García-Fandiño, R.; Montenegro, J.; RSC Chemical Biology 2021, 2, 503-https://doi.org/10.1039/d0cb00103a512.

56. “An Adhesive Peptide From the C-Terminal Domain of α-Synuclein for Single-layer Adsorption of Nanoparticles on substrates" Bhak, G.; Méndez-Ardoy, A.; Escobedo, A.;  Salvatella, X.; Montenegro, J.; Bioconjugate Chemistry 2020, 12, 2759-2766.

55. “Stronger Together: Multivalent Phage Capsids Inhibit Virus Entry" Gallego, I.; Lostalé-Seijo, I.; Montenegro, J.; ChemBioChem 2021, 22, 478-480

54. “Sequence Decoding of 1D to 2D Self-Assembing Cyclic Peptides" Díaz, S.; Insua, I.; Bhak, G.; Montenegro, J.; Chem. Eur. J. 2020, 26, 14765-14770.

53. “Synthetic Supramolecular Systems in Life-like Materials and Protocell Models" Insua, I.; Montenegro, J.; Chem 2020, 6, 1652-1682.

52. “Spatially controlled supramolecular polymerization of peptide nanotubes by microfluidics Méndez-Ardoy, A.; Bayón-Fernández, A.; Yu, Z.; Abell, C.; Granja, J.R.; Montenegro, J.; Angew. Chem. Int. Ed. 2020, 59, 6902-6908.

51. “Synthesis and Supramolecular Functional Assemblies of Ratiometric pH Probes” Méndez-Ardoy, A.; Reina, J. J.; Montenegro, J.; Chem. Eur. J. 2020, 26, 7516-7536.

50. “1D to 2D Self Assembly of Cyclic Peptides” Insua, I.; Montenegro, J.; J. Am. Chem. Soc. 2020, 142, 300-307.

49. “Detection of Oligomeric Amyloid Aggregates in Real-Time Using Metal Complexes” Jiang, B.; Aliyan, A.; Cook, N. P.; Augustine, A.; Bhak, G.; Maldonado, R.; Smith McWilliams, A. D.; Flores, E.; Mendez, N. G.; Godoy, F.; Montenegro, J.; Moreno-Gonzalez, I.; Martí. A. A.; J. Am. Chem. Soc. 2019, 141, 15605-15610.

47. “Messenger RNA delivery by hydrazone-activated polymers” Juanes, M.; Creese, O.; Fernandez-Trillo, F.; Montenegro, J.; MedChemComm 2019, 10, 1138-1144.

* Contribution to the 2019 Special Issue on Young Talents in Medicinal Chemistry.

46. “Péptidos penetrantes celulares: descripción, mecanismo y aplicaciones” Gallego, I.; Rioboo, A.; Montenegro, J.; Anales de Química 2019, 115, 9-21.

* Front Cover and invitation as Prize of Young Researchers of RSEQ.

45. “Glycosylated Cell Penetrating Peptides, GCPPs” Gallego, I.; Rioboo, A.; Reina, J. J.; Díaz, B.; Canales, A.; Cañada, F. J.; Guerra-Varela, J.; Sánchez, L.; Montenegro, J.; ChemBioChem 2019, 20, 1400-1409.

* Contribution to the 2019 Special Issue on ChemBioTalents

44. “Self-Assembled Micro-Fibres by Oxime Connection of Linear Peptide Amphiphiles” Booth, R.; Insua, I.; Bhak, G.; Montenegro, J.; Org. Biomol. Chem. 2019, 17, 1984-1991.

* Contribution to the 2018 Special Issue on Organic & Biomolecular Chemistry New Talent Themed Issue


43. “Where in the cell is our cargo? Current methods to study intracellular cytosolic localization.” Méndez-Ardoy, A.; Lostalé-Seijo, I.; Montenegro, J.; ChemBioChem 2018, 20, 488-498.

* Contribution to the 2018 Special Issue on Biosensing and Bioimaging

42. “Synthetic materials at the forefront of gene delivery” Lostalé-Seijo, I.; Montenegro, J.; Nat. Rev. Chem. 2018, 2, 258-277.

41. “Oligoalanine Helical Callipers for Cell Penetration” Pazo, M.; Juanes, M.; Lostalé-Seijo, I.; Montenegro, J.; Chem. Commun. 2018, 54, 6919-6922.

40. “Supramolecular Recognition and Selective Protein Uptake by Peptide Hybrids” Juanes, M.; Lostalé-Seijo, I.; Granja, J.; Montenegro, J.; Chem. Eur. J. 2018, 24, 10689-10698.

39. “Different Length Hydrazone Activated Polymers for Plasmid DNA Condensation and Cellular Transfection” Priegue, J., Lostalé-Seijo, I., Crisan, D., Granja, J., Fernández-Trillo, F., Montenegro, J. Biomacromolecules, 2018, 19, 2638-2649.

38. “pH-Triggered Self-assembly and Hydrogelation of Cyclic Peptide Nanotubes Confined in Water Micro-droplets” Méndez-Ardoy, A., Granja, J. R., Montenegro, J. Nanoscale Horizons, 2018, 3, 391-396.

37. “Novel Supramolecular Nanoparticles Derived From Cucurbit[7]uril and Zwitterionic Surfactants” Fernández-Rosas, J., Pessêgo, M., Acuña, A., Vázquez-Vázquez, C., Montenegro, J. Parajó, M., Rodríguez-Dafonte, P., Nome, F., Garcia-Rio, L. Langmuir, 2018, 34, 3485-3493.

36. “Glycosyl Aldehydes, New Scaffolds for the Synthesis of Neo-Glycoconjugates via Bio-orthogonal Oxime Bond Formation” Reina, Jose J., Rioboo, A., Montenegro, J. Synthesis, 2018, 50, 831-845.

* 2017 Bürgenstock Special Section 2017: Future Stars in Organic Chemistry)

35. “Peptide/Cas9 Nano-structures for Ribonucleoprotein Cell Membrane Transport and Gene Edition” Lostalé-Seijo, I.; Louzao, I.; Juanes, M.; Montenegro, J. Chem. Sci., 2017, 8, 7923-7931.

34. “Highlights from the 52nd EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2017” Montenegro, J., Phipps, R. Chem. Commun. 2017, 53, 9960-9966.

* 2017 Invitation for conference report of the   Bürgenstock Conference 2017.

33. “Poly(acryloyl hydrazide), a versatile scaffold for the preparation of functional polymers: synthesis and post-polymerisation modification” Crisan, D. N,; Creese, O.;  Ball, R,; Brioso, J. L.,; Martyn, B.; Montenegro, J.; Fernandez-Trillo, F. Pol. Chem. 2017, 8, 4576-4584.

32. “Supramolecular Functional Assemblies: Dynamic Membrane Transporters and Peptide Nanotubular Composites” Fuertes, A.; Juanes, M.; Granja. R. J.;  Montenegro, J. Chem. Commun., 2017, 53, 7861-7871.

31. “Hydrazone-modulated peptides for efficient gene transfection” Louzao, I.; García-Fandiño, R.; Montenegro, J. J. Mat. Chem. B, 2017, 5, 4426-2234.

* Contribution to the 2017 Emerging Investigators Issue

30.  “Tuning the Properties of Penetrating Peptides by Oxime Conjugation” Pazo, M.; Fernández-Caro, H.; Priegue, J. M.; Lostalé, I.; Montenegro, J. Synlett, 2017, 28, 924-928.

*  Contribution to the Euchems Young Emerging Investigators

29. "Membrane-Disrupting Iridium (III) Oligocationic Organometallopeptides." Salvadó, I., Ilaria, G., Montenegro, J., Martínez-Costas, J., Brea, J. M., Loza, M. I., Vázquez-López, M., Vazquez, E. Chem. Commun. 2016, 52, 11008-110011.

28. “In situ” Functionalized Polymers for siRNA Delivery”, Priegue, J. M.; Crisan, D. N.; Martínez-Costas, J;  Granja, J. R.; Fernandez-Trillo, F.; Montenegro, J. Angew. Chem. Int. Ed. 2016, 55, 7492-7495.

27. “Self-assembly of Silver Metal Clusters of Small Atomicity on Cyclic Peptide               Nanotubes”, Cuerva, M.; García-Fandiño, R.; Vázquez-Vázquez, C.; López-Quintela, M. A. Montenegro*, J.; Granja, J. R. ACS Nano, 2015, 9, 10834-10843.

26. “Cellular Uptake: Lessons from Supramolecular Organic Chemistry”, Gasparini, G.; Bang, E.-K.; Montenegro, J.; Matile, S. Chem. Commun. 2015, 51, 10389-10402

25. “Membrane-Targeted Self-Assembling Cyclic Peptide Nanotubes” Rodríguez-Vázquez, N.; Ozores, H. L.; Guerra, A.; González-Freire, E.; Fuertes, A.; Panciera, M.; Priegue, J. M.; Outeiral, J.; Montenegro, J.; García-Fandiño, R.; Amorín, M. and Granja, J. R. Curr. Top. Med. Chem. 2015, 14, 2647-2661.

24. “Single-nucleotide-resolution DNA differentiation by pattern generation in lipid bilayer membranes” Priegue, J. M.; Montenegro,* J; Granja, J. R. Small, 2014, 10, 3613-3618.

23. “One-step chemoselective conversion of tetrahydropyranyl ethers to silyl-protected alcohols” Bergueiro, J., Montenegro, J.,* López, S., Saa, C. RSC Advances, 2014, 4, 14475-14479.

22. “Coupling of Peptides and Carbon Nanotubes” Montenegro, J.,* Vázquez-Vázquez, C., Kalinin, A., Geckeler, K. E., & Granja, J. R. J. Am. Chem. Soc., 2014, 136, 2484-2491.

21.“Ion Channel Models Based on Self-Assembling Cyclic Peptide Nanotubes.” Montenegro, J.; Ghadiri, M. R.; Granja, J. R. Acc. Chem. Res., 2013, 46, 2955-2965.


20. “Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts.” Gehin, C.; Montenegro, J.; Bang, E.-K.; Cajaraville, A.; Takayama, S.; Hirose, H.; Futaki, S.; Matile, S.; Riezman, H. J. Am. Chem. Soc., 2013, 135, 9295-9298.

19. "Synthesis of 11-cis-retinoids by Hydrosilylation-Protodesilylation of an 11, 12-Didehydro Precursor: Easy Access to 11- and 12-Mono- and 11, 12-Dideuteroretinoids." Bergueiro, J.; Montenegro, J.; Saá, C.; López, S. Chem. Eur. J., 2012, 18, 14100-14107.

18. “Synthesis of an Enlarged Library of Dynamic DNA Activators with Oxime, Disulfide and Hydrazone Bridges.” Montenegro, J.; Bang, E.-K.; Sakai, N.; Matile, S. Chem. Eur. J., 2012, 18, 10436-10443.

17. “Cross-Coupling Reactions of Organosilicon Compounds in the Stereocontrolled Synthesis of Retinoids.” Bergueiro, J.; Montenegro, J.; Cambeiro, F.; Saá, C.; López, S. Chem. Eur. J., 2012, 18, 4401-4410.

16. “Total Synthesis of Millingtonine A” Wegner, J.; Ley, S. V.; Kirschning, A.; Hansen, A.-L.; Montenegro Garcia, J.; Baxendale, I. R. Org. Lett., 2012, 14, 696-699.

15. “Recent Progress with Functional Biosupramolecular Systems.” Doval, D. A.; Areephong, J.; Bang, E.-K.; Bertone, L.; Charbonnaz, P.; Fin, A.; Lin, N.-T.; Lista, M.; Matile, S.; Montenegro, J.; Orentas, E.; Sakai, N.; Tran, D.-H.; Jentzsch, A. V. Langmuir, 2011, 27, 9696-9705.

14. “Pattern generation with synthetic sensing systems in lipid bilayer membranes.” Takeuchi, T.; Montenegro, J.; Hennig, A.; Matile, S. Chem. Sci., 2011, 2, 303-307.

12. “Conceptually new entries into cells.” Montenegro, J.; Gehin, C.; Bang, E.-K.; Fin, A.; Doval, D. A.; Riezman, H.; Sakai, N.; Matile, S. Chimia, 2011, 65, 853-858.

13. “Synthetic polyion-counterion transport systems in polymersomes and gels.” Montenegro, J.; Braun, J.; Fischer-Onaca, O.; Meier, W.; Matile, S. Org. Biomol. Chem., 2011, 9, 6623-6628.

11. “Comprehensive screening of octopus amphiphiles as DNA activators in lipid bilayers: implications on transport, sensing and cellular uptake.” Montenegro, J.; Fin, A.; Matile, S. Org. Biomol. Chem., 2011, 9, 2641-2647.

10. “Recent synthetic transport systems.” Matile, S.; Vargas Jentzsch, A.; Montenegro, J.; Fin, A. Chem. Soc. Rev., 2011, 40, 2453-2474.

9. “Anionic Activators for Differential Sensing with Cell-Penetrating Peptides.” Montenegro, J.; Matile, S. Chem. Asian J., 2010, 6, 681-689.

8. “Dynamic Octopus Amphiphiles as Powerful Activators of DNA Transporters: Differential Fragrance Sensing and Beyond.” Montenegro, J.; Bonvin, P.; Takeuchi, T.; Matile, S. Chem. Eur. J., 2010, 16, 14159-14166.


7. “Experimental evidence for the functional relevance of anion-π interactions.” Dawson, R. E.; Hennig, A.; Weimann, D. P.; Emery, D.; Ravikumar, V.; Montenegro, J.; Takeuchi, T.; Gabutti, S.; Mayor, M.; Mareda, J.; Schalley, C. A.; Matile, S. Nat. Chem., 2010, 2, 533-538.

6. “Hiyama Cross-Coupling Reaction in the Stereospecific Synthesis of Retinoids.” Montenegro, J.; Bergueiro, J.; Saá, C.; López, S. Hiyama. Org. Lett., 2009, 11, 141-144.

5. "Counterion-Activated Translocation of Polyanions in Lipid Bilayers" Toshihide Takeuchi, Javier Montenegro, Stefan Matile. Chimia, 2009, 63, 469.

3. “Functional Biosupramolecular Systems.” Montenegro, J.; Hennig, A. Chimia, 2009, 63, 881-884.

4. “Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones.” Ura, Y.; Al-Sayah, M.; Montenegro, J.; Beierle, J. M.; Leman, L. J.; Ghadiri, M. R. Org. Biomol. Chem., 2009, 7, 2878-2884.

2. “Highly Convergent, Stereospecific Synthesis of 11- cis-Retinoids by Metal-Catalyzed Cross-Coupling Reactions of (Z)-1-Alkenylmetals.” López, S.; Montenegro, J.; Saá, C. J. Org. Chem., 2007, 72, 9572-9581.

1.“Synthesis of N-Heteroaryl Retinals and their Artificial Bacteriorhodopsins.” López, S.; Rodríguez, V.; Montenegro, J.; Saá, C.; Alvarez, R.; Silva López, C.; de Lera, A. R.; Simón, R.; Lazarova, T.; Padrós, E. ChemBioChem, 2005, 6, 2078-2087.

68. "Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides" Chen Y., Barba-Bon, A., Grüner, B., Winterhalter, M., Aksoyoglu, M. A., Pangeni, S., Ashjari, M., Brix, K., Salluce, G., Folgar-Cameán, Y., Montenegro, J., Nau, W., W. J. Am. Chem. Soc., 2023, 145, 24, 13089–13098.

69. "Photoswitchable Calixarene Activators for Controlled Peptide Transport Across Lipid Membranes" Martins, J., Raimundo, B., Rioboo, A., Folgar-Cameán, Y., Montenegro, J., Basílio, N., J. Am. Chem. Soc., 2023, 145, 24, 13126–13133

70. "Self-Assembly of Cyclic Peptide Monolayers by Hydrophobic Supramolecular Hinges" Insua, I., Cardellini, A., Díaz, S, Bergueiro, J., Capelli, R., Pavan, G. M.,  Montenegro. J., Chem. Sci. 2023, 14, 14074-14081..